597 zoekresultaten voor “immunity infection and tol” in de Publieke website
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Systems vaccinology: molecular signatures of immunity to Bordetella pertussis
Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz
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extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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Noa TolFaculteit Rechtsgeleerdheid
n.i.tol@law.leidenuniv.nl | +31 71 527 2727
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Pulling the strings on anti-cancer immunity
Promotores: J. Jonkers, K.E. de Visser
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Aranka van Tol
Faculteit der Geesteswetenschappen
a.a.m.van.tol@hum.leidenuniv.nl | +31 71 527 2125
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Jeffrey van Tol
Expertisecentrum SOZ
j.van.tol@sea.leidenuniv.nl | +31 71 527 6404
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Daan van TolWiskunde en Natuurwetenschappen
d.j.c.van.tol@lic.leidenuniv.nl | +31 71 527 2727
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Kirsten van der TolFaculteit Rechtsgeleerdheid
c.g.m.van.der.tol@law.leidenuniv.nl | +31 71 527 8787
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Maarten van Tol
Faculteit Geneeskunde
m.j.d.van_tol@lumc.nl | +31 71 526 3331
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Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches
Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.
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Computational modeling of mycobacterium infection and innate immune reponse in zebrafish
Promotor: Prof.dr. J.N. Kok
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Bart RoepFaculteit Geneeskunde
b.o.roep@lumc.nl | +31 71 526 3869
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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C1q and anti-C1q autoantibodies in (auto)immunity
Promotie
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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bridges: a multidisciplinary approach to controlled human hookworm infection
Promotie
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Control of Western flower thrips through jasmonate-triggered plant immunity
We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.
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innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Innate immunity, developmental speed and their trade-offs in two hexapod models
This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.
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Chemokine signaling mechanisms underlying inflammation and infection control: insights from the zebrafish model
This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Cornelis HokkeFaculteit Geneeskunde
c.h.hokke@lumc.nl | +31 71 526 5065
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Construction and exploration of modular goldnanoparticles for glycan-based immune-interventions of worm infections
Chiodo
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Philine Hendriks-van den Tol
Faculteit Geneeskunde
j.p.h.hendriks-van.den.tol@umail.leidenuniv.nl | +31 71 526 3052
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Even voorstellen: Jonas van Tol
Sinds 1 augustus is Jonas van Tol als UD maritieme geschiedenis verbonden aan het Instituut voor Geschiedenis.
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Customary International Criminal Law and Head of State Immunity by Judge Chile Eboe-Osuji
On 12 September 2019, Judge Chile Eboe-Osuji, President of the International Criminal Court (ICC), delivered a lecture on Customary International Criminal Law and Head of State Immunity to open the academic year for the Advanced LL.M. Programmes in Public International Law & International Dispute Settlement…
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Cytokine-mediated regulation of immunity during persistent viral infection
Promotie
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cell-mediated immune modulation in experimental Rheumatoid Arthritis and Atherosclerosis
In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.
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Cornelis van KootenFaculteit Geneeskunde
c.van_kooten@lumc.nl | +31 71 526 2148
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Frank Baas
Faculteit Geneeskunde
f.baas@lumc.nl |
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Bizar tollende dubbelster verklaart 30 jaar oud raadsel
Een internationaal team onder leiding van Leidse sterrenkundigen heeft ontdekt waardoor de twee sterren van dubbelster DI Herculis zo bizar om elkaar heen bewegen. In een artikel in Nature verklaren ze de rare baanbewegingen die zelfs voor Einsteins relativiteitstheorie een probleem vormden.
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Tollend elektron op de nanometer nauwkeurig te verplaatsen
Het is een team van onderzoekers gelukt om een enkel spinnend elektron te positioneren op een chip met een precisie van enkele nanometers. Hiermee ligt de weg open naar quantumchips met nano-elementen naar keuze. De resultaten zijn gepubliceerd in het gerenommeerde Applied Physics Letters.
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Studies on molecular basics of metabolic syndrome in zebrafish
The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.
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Rubicon voor Joris van den Tol om onderzoek te doen aan Harvard University
Joris van den Tol, docent International Studies, heeft een NWO Rubiconbeurs gekregen om twee jaar lang onderzoek te doen aan Harvard University (Verenigde Staten). Hij zal onderzoeken hoe 17e-eeuwse Nederlandse handelaren en Engelse plantagehouders samenwerkten in een trans-Atlantische lobbyallianti…
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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Wim van AnrooijFaculteit der Geesteswetenschappen
w.van.anrooij@hum.leidenuniv.nl | +31 71 527 2121
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Musems, Collections and Society | Yearbook 2020
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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Musems, Collections and Society | Yearbook 2021
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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Studieprogramma
Bij Biomedische wetenschappen word je opgeleid tot wetenschapper in het biomedisch veld. Wat houdt dat eigenlijk precies in en wat leer je allemaal in de bachelorfase?
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Terrorism and Political Violence
Begrijpen van het evoluerende landschap van extremisme in de 21e eeuw.
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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Citizenship, Migration and Global Transformations
Europese burgers worden geconfronteerd met uitdagingen op het gebied van globalisering, migratie, technologische ontwikkelingen en klimaatverandering. Deze uitdagingen vergen het uiterste van onderlinge internationale en intergenerationele solidariteit, wat rechtstreeks betrekking heeft op de grondslagen…
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Novel mediators of anti-tumor immunity
Promotie
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Ice and Gas in Protostellar Clouds and Planet-forming Disks
This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.